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Differential targeting of GSH1 and GSH2 is achieved by multiple transcription initiation: Implications for the compartmentation of glutathione biosynthesis in the Brassicaceae

HDACs mitigate cancer chemotherapy resistance by inhibiting the proliferation of cancer stem cells though regulating oncogene promoters

Equally, translating these systems into larger animal models and early phase clinical trials will be critical to validate safety, dosing, and long-term efficacy in ALS and AD