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Although several studies have supported the view that CX36 may also be involved in epileptogenesis, there is still an ongoing controversy associated with the alterations of CX36 at different developmental stages of human and animal models of epileptogenesis (Wu et al., 2018)

the endosomolytic component may contain a chemical group (e.g., an amino acid) which will undergo a change in charge or protonation in response to a change in pH

10.1186/s40168-021-01125-7 125

Disclosures: Jessica Mellinger: GlaxoSmithKline: Advisor, Tingting Liu: Nothing to Disclose, Haila Asefa: Nothing to Disclose, Patricia Bloom: Vedanta Biosciences: Research grant, Nexilico: Consultant, Sal Giorgi: Nothing to Disclose, Brenda Curtis: Nothing to Disclose 2219 DISTRIBUTION OF ORGANISMS IN PATIENTS WITH SPONTANEOUS BACTERIAL PERITONITIS: A VETERAN'S HEALTH COHORT STUDY Nadim Mahmud 1 Natalia Salinas Parra 2 Aaron Hecht 3 David Kaplan 3 Marina Serper 4 , 1 Hospital of the University of Pennsylvania, 2 Hospital of the University of Pennyslvania, 3 University of Pennsylvania, 4 University of Pennsylvania Health System Background: Spontaneous bacterial peritonitis (SBP) is a common complication of decompensated cirrhosis with a high mortality rate

doi: 10.1097/HS9.0000000000000165