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10.1210/en.2014-1765 30 DingH.ZhangJ.ZhangF.ZhangS.ChenX.LiangW.et al (2021)

Contraindications Absolute contraindications include Wilsons Disease or other copper metabolism disorders, known copper allergy or hypersensitivity, and pregnancy or breastfeeding (no safety data exists for systemic use during these periods)

The lack of information is because of insufficient human clinical trials

Heres a quick look at the ingredients: Ashwagandha: 1,000mg KSM-66 Shilajit: 500mg PrimaVie Fenugreek extract: 500mg Quercetin: 250mg DIM: 250mg Longjack: 100mg LJ100 Boron: 10mg Two things stand out about this formula

While further research is essential to determine if a specific dietary intake of ergothioneinecontaining foods can effectively protect the heart, the preliminary results from this large-scale study are encouraging, suggesting that foods rich in ergothioneine could be a valuable tool for promoting heart health

Quercetin aglycone is then primarily metabolized in the gastrointestinal tract (Graf et al., 2006)