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The serial ctDNA analyses detected an emergence of mismatch repair gene MSH2 and MSH6 gene mutations, which is associated with hypermutation and potential development of TMZ resistance during treatment with TMZ

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YY1 was also the only gene found to be differentially expressed between DGCs and GSCs and will be the focus of further discussion

The activities of GPX and GST were evaluated according to (Nagalakshmi and Prasad 2001)

Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis

While K48 is preserved, UBB+1 cannot form polyubiquitin chains because of the absence of a C-terminal Gly