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In Biopharmaceutics and Pharmacokinetics Considerations (Vol

Research focuses on: receptor-mediated growth signaling protein synthesis pathways systemic anabolic activity This distinction is central to their research applications

One in vitro study highlighted the potential efficacy of SF in mitigating the effects of placental insufficiency on neuronal cells (56)

see also, Snijders et al., 2021)

Therefore, although our review aimed to broaden our knowledge on the clinical applications of ALA, further randomized, double-blind, placebo-controlled clinical trials with adequate sample sizes, homogeneity of population studied, statistical power, as well as longer duration are (still) needed to confirm the clinical benefit of this multifunctional compound and extend its use in routine medical practice

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