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The neuronal isoform 1 of Dynamin and FCHSD2, a protein that promotes actin polymerization at the base of Clathrin-coated pits [25], were both shown to be phosphorylated as downstream targets of oncogenic signaling cascades that stimulate endocytosis [26][27] making it likely that they also constitute regulatory points during stress

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7c) and retains hydrophobic interactions in the vicinity of subsite C

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220 , 221 , 222 In addition, some studies suggest that treatments such as vagus nerve stimulation may have some effect on improving symptoms of PD by modulating signaling in the gut-brain axis