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Cancer Drug Targets 24

Network analysis of microbial co-occurrence patterns Network analysis across taxonomic levels revealed key microbial interactions and potential keystone taxa (Figure S6)

Adding higher or lower concentration of standard may cause inconsistent signal or false positive

doi: 10.1038/s41418-022-01003-1 205 ZoghbiHYBeaudet al

For instance, in glucose-deficient glioblastoma, heightened SLC7A11 expression leads to the generation of ROS and oxidative stress through the consumption of intracellular NADPH during the conversion of imported L-cystine to L-cysteine ( in vivo , within a tumor microenvironment, where the metabolic reprogramming associated with altered SLC7A11 expression was evident ( in vivo experiments demonstrated that heightened SLC7A11 expression facilitated localized tumor growth while impeding tumor migration

There have been reports of adverse effects such as nausea, diarrhea, and abdominal cramping