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There was also a profound increase of GSTs expression after Dox exposure

Recent research has underscored the need to comprehend the molecular mechanisms of disulfidptosis, particularly regarding cancer treatment, as targeting disulfide metabolism could open up new therapeutic strategies ( FIGURE 1 3.2 Specific mechanism of SLC7A11 in disulfidptosis The abnormal accumulation of intracellular disulfides in SLC7A11 high cells during glucose deprivation triggers a novel form of cell death, which is distinct from both the apoptosis and ferroptosis

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Zhang KL, Zhu WW, Wang SH, Gao C, Pan JJ, Du ZG, et al

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