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However, unlike voltage-gated K + channels, in TRPM2 (like in other TRPs), the voltage sensor-like domain lacks the conserved array of positively charged arginine and lysine and interacts with the S5-S6 of the adjacent subunit in a domain-swapping manner (Xia et al., 2019)

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Haroon E, Raison CL, Miller AH (2012)

C-terminal domain of a hevein-like protein from wasabia japonica has potent antimicrobial activity

It has been studied in relation to fat metabolism and thermogenesis

Its for specific cases where oral or muscle injections arent enough