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It can lead to dark urine as well as: dry mouth and lips thirst dizziness or weakness trouble swallowing dry food constipation fatigue Children, older adults, and people living with severe illnesses, such as cancer, are more prone to dehydration

Furthermore, the relevance of this to the pathogenesis of disease is controversial ( In the meantime, the majority of research on mitophagy in the nervous system has concentrated on the molecular pathogenesis and potential therapeutic targets, while there is considerable debate surrounding the targets of mitophagy, the exact mechanism of receptor-mediated mitophagy, and how to address it