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Moreover, the models discrimination and clinical relevance were visualized using calibration curves and ROC curve analysis

These ROS, in conjunction with lipid peroxidation products such as 4-HNE and MDA, facilitate the release of mtDNA, which activates TLR9 and the NLRP3 inflammasome in Kupffer cells [11]

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Background Reduced Glutathione (GSH) is a tripeptide naturally synthesized in human cells, consists of glutamic acid, cysteine and glycine, contains sulfhydryl (-SH), is widely distributed in each organ of a human body, and has important effects on maintaining the biological function of cells and protecting the integrity of cell membranes

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