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Individuals who have deletions of the entire NF1 gene have an increased risk of facial dysmorphism, mental retardation, early appearance of neurofibromas, and the presence of plexiform neurofibromas.1 In addition, individuals who have a specific 3 base pair in-frame deletion in exon 17 of the NF1 gene may have caf-au-lait spots, intertriginous freckling and Lisch nodules, but do not develop cutaneous, subcutaneous or plexiform neurofibromas

Anthony RM, MacLeay JM, Jewell DE, Brejda JJ, Gross KL

TAT peptide is a common type of cell penetrating peptides (CPPs) that efficiently deliver extracellular biomacromolecules into cytoplasm

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reuteri secretes a highmolecularweight mucus-binding protein (MUB) that is pivotal for host attachment

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