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For all experiments, if not otherwise stated, DBA1/J female mice (8 weeks old) were used and purchased from Janvier Labs

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Dose reduction community sources describe halving the per-injection dose when flushing or metallic taste becomes too intrusive, then re-evaluating at 2 weeks

Studies revealed that in aged rhesus monkeys (20-26 years), Epithalon increased melatonin levels more than 3-fold compared to baseline, restoring circadian patterns characteristic of younger animals

Anti-inflammatory activity: Demonstrates reduction in inflammatory markers in laboratory models