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Grove JI, Aithal GP

The role of hypoxia-inducible factor-2 in digestive system cancers

doi: 10.1002/bmc.5698 96 JoviMDAgatonovic-KustrinSMRistivojeviPMTrifkoviJMortonDW

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While the most well-known property of IGF-LR3 is this muscle maintenance and building effect that helps many folks look better than their built-in genetics intended, there are several other benefits of IGF-LR3, including: Increased muscle retention Increased physical performance Faster recovery Increased drive Increased effectiveness of the anabolic cycle Rapid fat loss Decreased effects of aging Improved testicular health More rapid sleep onset and body recovery during sleep Bodybuilders first started using this stuff when they found themselves spending hours in the gym each week, eating plain chicken piled on broccoli (with no salad dressing of course), only to find themselves unable to get that extra little bit of fat loss or muscle gain

Thyroid function tests (TSH, T3, T4) are particularly relevant for semaglutide patients, as thyroid conditions are both a common contributor to weight management difficulty and a consideration for treatment eligibility