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Herein we summarize the efforts the last three decades to transform the hexapeptide into more drug-like peptidemimetics acting at its receptor(s)

Below is an example of introducing non natural amino acids: R1-NH 2 + C 10 H 10 N 2 O 2 -OH C 10 H 10 N 2 O 2 -R1 + H 2 O It should be noted that due to the different structures of the amino acid side chain group R1, the reaction conditions, solvents, reagents, etc

Badenhorst, T., Svirskis, D., Merrilees, M., Bolke, L., & Wu, Z

Critical note: use separate vials and syringes for each peptide since mixing peptides in the same syringe risks stability issues

See Batch Specific COA Below) Form: Synthetic Peptide Powder Available in 5 mg or 10 mg vials This product is intended strictly for laboratory research use only

Vandael D, Gounko NV (2019) Corticotropin releasing factor-binding protein (CRF-BP) as a potential new therapeutic target in Alzheimers disease and stress disorders