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Adverse reactions related to hypotension (hypotension, orthostatic hypotension, and decreased blood pressure) were reported in 1.3% of semaglutide-treated patients versus 0.4% of placebo-treated patients during clinical trials of the semaglutide injection for weight management

doi: 10.1038/onc.2017.146 26 Rojo de la VegaMChapmanEZhangDD

It would be in a really small niche circuit, whereas now it is advertised and promoted, and companies are shouting about it, which I personally dont agree with

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Its become a dirty word because many people, like you are chronically inflamed, and thats actually more related to obesity, body fat is very involved in the inflammatory cascade