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The patient in our case report had the risk factors of having a popliteal cyst, knee pathology, as well as DVT

However, doctors may investigate further when low B12 appears alongside symptoms that suggest a more serious underlying illness

He showed significant symptomatic and hematologic improvement and was discharged in a stable condition with advice for gastroenterology follow-up

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Studies have shown that appropriate supplementation of folic acid and VitB12 has a protective effect on BRCA-related breast cancer, especially in BRCA1 mutation carriers [48]