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An intact intestinal barrier plays a crucial role in upholding gastrointestinal function and overall human health (Di Sabatino et al., 2023)

OToole et al., 2000

We have previously shown that under calorie restriction (CR), mitochondrial deacetylase Sirt3 deacetylates and activates IDH2 in mouse cochlea 3

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These cells were then further passaged as single cells to generate colonies that later were hand-picked for achieving a homogenous cell population

R.ChessellI.CrookB.et al