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Available from: [DOI] [PubMed] [Google Scholar] 149.Gaetke LM, Chow-Johnson HS, Chow CK

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found that baicalin inhibited the phosphorylation of p38 MAPK, which in turn suppressed the expression and activity of PGC-1.Acetyl-CoA carboxylase (ACC) is was a key enzyme in fatty acid synthesis, and baicalin alleviated the inhibitory effects of high-fat diet-induced phosphorylation of skeletal muscle ACC and AMP-activated protein kinase (AMPK) (Xi et al., 2016)

Many medications are available to aid in symptom management, and surgical options are available when medications alone are no longer feasible

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