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Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

Monosodium urate (MSU) crystals deposited in synovial tissue can interact with the innate immune system, triggering an inflammatory response that results in typical symptoms of gout, including pain, swelling, and redness [7]

Multiple other transporters and enzymes, including the availability of GSSG reductase, thioredoxins, and activity of glutathione transferases are also involved in maintenance of the intracellular GSH-GSSG balance, which could be evaluated in the future

The active form of B12 in this formulation is methylated and, thus, highly bioavailable

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We assumed clinicians who may have submitted the Optimal Care for Patients with Episodic Neurological Conditions MVP or the Supportive Care for Neurodegenerative Conditions MVP will instead submit the Quality Care for Patients with Neurological Conditions MVP