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The amino acid residues involved in interactions with FAD molecules that were discovered by docking (Fig

That's a real finding in real people and it matters, but the sample size, follow-up duration, and level of independent replication are in a different category from finasteride's evidence base

Cell Death Differ 29(6):10941106

Thus, trapping AP sites and blocking their repair by APE1 will result in cytotoxicity

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This allows predicting the drug efficacy in these various patients and cell line backgrounds and estimating the number of patients needed to be treated before seeing a positive outcome (Number Needed to Treat, NNT)