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Future studies on the role of oxidative stress in the comorbidity of both diseases should further clarify the nature of these processes, identify common mechanisms involved in the course of diseases, and consider the role of antioxidants in the development of therapeutic strategies

With disruption of the mitochondrial membrane potential, these aggregates do not form, and JC-1 remains in its monomeric form emitting a green fluorescence (Ex497/Em528)

10.1016/j.jinorgbio.2015.09.003 58 SteinbrennerH.SiesH

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Methods Sixteen weeks old nulligravid female Wistar rats were housed at a constant temperature (22C) in a 12 hours light and dark cycle environment with free access to food and drinking water

Conclusion Therapeutic peptides represent a promising yet evolving area in orthopaedics