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Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment

Valencia, A

In the atrophic (dry) form of AMD, cellular debris called drusen accumulate between the retina and the choroid

Ubiquitin-specific protease 24 (USP24) promotes ferroptosis by activating NF-B pathway, upregulating ACSL4 levels, and reducing SLC7A11 and FTH1 levels, thereby decreasing the antioxidant capacity of cardiomyocytes

Studies using animal models of allergen-induced lung inflammation have shown that mitochondrial dysfunction, involving altered mitochondrial ROS production, morphology and mitophagy, may drive asthma pathology (Zhang et al., 2020

AT2R, angiotensin type 2 receptor