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Immunological factors play a prominent role in the development of this disease (204)

Inefficiency of the phagocytosis process leads to the formation of residual lipid-protein granules that cannot be degraded, known as lipofuscin, and generation of ROS occurs from the constant exposure of lipofuscin to light and oxygen tension 1

Brain metastasis of breast cancer can be located in the parenchymal brain (around four-fifths) or in leptomeningeal region (109)

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