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In addition to the docking score and the RMSD of GSSG, we also considered the S-S distance between GSSG and each cysteine residue in GLRX, as a short distance is required for the consequent glutathionylation process

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In the PI3K/Akt/mTOR pathway, receptor autophosphorylation recruits and activates phosphoinositide 3-kinase (PI3K), which phosphorylates membrane phospholipids to generate PIP3

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