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For researchers using oral capsules, taking the compound 30 to 60 minutes before meals in a fasted state may enhance fat oxidation effects, though this recommendation is based on theoretical considerations rather than controlled studies

The concentrations used, the cell types tested, and the exposure conditions do not directly translate to what happens when a human applies a cream or injects a solution

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Researchers report that skin conditions like eczema may show improvement in inflammation and clarity within 3 to 6 weeks of consistent application