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It will nevertheless be understood that no limitation of the scope of the invention is thereby intended, and alterations and modifications in the illustrated invention, and further applications of the principles of the invention as illustrated therein are herein contemplated as would normally occur to one skilled in the art to which the invention relates

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NF-kB controls the expression of hundreds of inflammation-related genes, including TNF-alpha, IL-1beta, IL-6, IL-8, COX-2, and dozens of adhesion molecules and chemokines that drive the inflammatory cascade

If sterile water was used, its lifespan is reduced to about 24 hours