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Whether or not (and how) glutamine-glutamate metabolism of the different isoforms dictates the fate of the metabolites further down the TCA cycle needs further investigation, as well as the potential preferential role of GAC in glutamine dependency over KGA

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& Hendriks, J

Using a TH-tagged intracellular marker, the transcriptomic profiles of iPSC-derived DA neurons revealed high similarity to the profile of post-mortem human mDA neurons