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Laboratory studies show GHK-Cu treatment results in enhanced capillary-like tube formation in three-dimensional culture systems, with treated endothelial cells forming more extensive networks with improved branch points and connectivity compared to untreated controls, indicating promotion of both early vessel sprouting and later network organization phases

Studies in rabbits with partially healed bone defects show significant improvement with BPC-157 injections, yielding effects comparable to bone marrow or cortical graft procedures [11]

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Common modification methods include the introduction of non natural amino acids, cyclization of peptide chains, and glycosylation of peptide chains