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Randomized clinical trials (RCTs) were eligible, while combination therapy studies were included if GSHs effect could be isolated

A key redox-signaling pathway present in microglia is the NF-B pathway

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Stenmark et al., 2021)

Glutathione system activator Other than providing raw materials for the GSH system, another antioxidant strategy that activates the glutathione system is often achieved through medicinal therapy

It is important to note that a recent study revealed the opposite result with high doses of atorvastatin (40 m) in human cardiomyocytes and murine skeletal muscle cells, which is consistent with the adverse muscle effects of atorvastatin [229]