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1 In the past 50 years, the study of the toxic effects of heavy metals in humans has gained particular importance, since large quantities of these products, discarded as part of the industrial activity, are not biodegradable and persist in the environment for long periods of time

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Supplementation with 3 PUFAs enriched in DHA and EPA has been shown to promote the generation of PRLMs, including RvE1, RvD1, LXB, 18-HEPE, and 17-HDHA, enhancing anti-inflammatory and tissue-repair activity [83]

Di Mattia T, Martinet A, Ikhlef S, McEwen AG, Nomin Y, Wendling C, Poussin-Courmontagne P, Voilquin L, Eberling P, Ruffenach F, Cavarelli J, Slee J, Levine TP, Drin G, Tomasetto C, Alpy F (2020a) FFAT motif phosphorylation controls formation and lipid transfer function of inter-organelle contacts

3 and Supplementary Tables S5 and S6)