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Vitamin C injections are generally well tolerated at medically appropriate doses, but high doses can lead to iron overload, kidney stones, and kidney damage

For instance, single-cell RNA sequencing of microglia in germ-free vs colonized mice with neurodegenerative pathology can pinpoint microglial genes influenced by the microbiome

Mulliez E

Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells

& Stenberg, G

Therefore, we assumed that a sampling of the most common species found in the human GI tract should reasonably approximate the biochemical diversity of the murine gut microbiota