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For instance, peptides like Kisspeptin and GnRH help keep these hormone cycles on track

By virtue of their ankyrin repeat domains, the IB proteins mask the nuclear localization signals (NLS) of NF-B proteins and keep them sequestered in an inactive state in the cytoplasm

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"G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis"