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PET imaging studies show that increased CNS ketone intake rises linearly with serum concentration, with reciprocal reductions in glucose utilization, at approximately 1.02.0 mM serum -hydroxybutyrate [35, 37, 112]

BMI did not differ between males and females, thus not explaining the observed differences between genders (Supplementary figure 2t)

In general, weight control, improved dietary patterns and lifestyle modifications can prevent the development of metabolic syndrome and MASLD (374)

Surprisingly, adding exogenous GSH to the WT accelerated roGFP2 re-oxidation, but not in a dsbA strain