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It can abstract hydrogen atoms from the deoxyribose sugar backbone, leading to strand breaks, or add to the double bonds of DNA bases, resulting in base modifications such as 8-hydroxydeoxyguanosine (8-OHdG) [28]

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[63] first reported the existence of G protein-coupled receptor (GPCR) GLP-1R in human hepatocytes in 2010, and provided evidence to prove the direct effects of GLP-1 protein on cells

Gumucio JP, Mendias CL

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[124] reported that after Novo-Helisen-Depot SCIT treatment, the levels of sIgE, Th2-related cytokines, Th17-related cytokines, and the percentage of peripheral eosinophils decreased significantly