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By virtue of this influence, GSH production encounters inhibition, ushering in a cascade of cellular responses (Yang et al., 2014)

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when GC is activated, its catalytic intracellular domain can catalyze the decomposition of guanosine triphosphate, which leads to an increase in cyclic guanosine monophosphate (cGMP) levels in the cytoplasm and causes vascular smooth muscle relaxation through the cGMP-protein kinase A pathway (77)

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Ecotoxicol Environ Saf 230:113135

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Anti-hypertensive angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients

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The mean age was 57 years, and 52% were elderly

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