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Bronchial spasm or exacerbation of asthma have been reported with postmarketing use of the ophthalmic solution

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When vitamin B 12 concentration was examined as a continuous variable (data not shown), higher concentrations (per unit increased in blood B 12 concentrations) were associated with a decreased likelihood of incident depression symptoms (OR 099 (95 % CI 097, 099)

WHO 2011 guidance on the use of HbA1c in the diagnosis of diabetes mellitus adopted in the UK and reflected in NICE NG28 and NICE diabetes pathways specifies that HbA1c should not be used for diagnosis when conditions affecting red blood cell turnover or haemoglobin are present

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