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In contrast, the passive diffusion process of B 12 absorption normally a very small portion of total absorption of the vitamin from food consumption may exceed the haptocorrin- and IF-mediated absorption when oral doses of B 12 are very large, with roughly 1% efficiency

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Dimeric compounds are promising for simultaneously targeting dual binding domains, enhancing molecular recognition precision and consequently optimizing reaction dynamics and biochemical selectivity 13,14

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