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MedComm, 6 (12), e70540

Pharmaceuticals 13:314

The RIG-I signaling pathway is activated by short RNA duplexes (at least 10 nucleotides in length) and blunt-ended double-stranded RNAs (dsRNAs) bearing a 5-triphosphate (5-ppp) moiety, a feature commonly found in pathogenic RNAs