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However, oral supplementation may be limited by: Gastrointestinal intolerance Malabsorption syndromes Nausea or reduced appetite Medication-related absorption changes IV B-complex: Bypasses gastrointestinal absorption Allows predictable uptake Can be combined with hydration and other supportive nutrients May be considered when oral options are ineffective or poorly tolerated When B-Complex IV Therapy May Be Appropriate B-complex IV therapy is not intended for routine or indefinite use

Journal of Neurosurgery , 81 (3), 350353

This significant dose-limiting side effect can impact various parts of the gastrointestinal tract, primarily affecting the small intestine and the oral and oropharyngeal mucosal linings [74, 78, 79]

Exposure to fine particulate air pollution causes vascular insulin resistance by inducing pulmonary oxidative stress

2018;314:G378G387

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