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Regulation of DNA methylation by glucose metabolism Although traditional views emphasize the one-way regulatory effect of DNA methylation on metabolism [65], recent studies have shown that in thyroid cancer, the reprogramming of glycolysis may instead drive abnormal DNA methylation, providing a new theoretical perspective for targeted intervention (Fig

Continued technological advances in genomics, proteomics, and the availability of animal models with cell-specific KOs of particular ligands or receptors will surely aid in the quest to understand the precise roles that the insulin family of growth factors plays in reproductive development and function