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In contrast, preclinical models often utilise mucosal biopsies or caecal contents to capture spatial and mechanistic nuances in hostmicrobiota interactions [90, 91] (Fig

Funding This work was supported by grants from the National Natural Science Foundation of China (81700055), the Outstanding Talent Research Funding: Xuzhou Medical University (D2016021), the Natural Science Foundation of Jiangsu Province (BK20160229), Shandong Province Traditional Chinese Medicine Science & Technology Project (no

Hong YM

HDAC1-3 can reduce the Kla levels of Hla (20,24,33) and n-Hla (26,30,34), acting as negative regulators in this process

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