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11% for T47D cells), then serine synthesis may be sufficient to exert at least some negative feedback on glycolysis despite its minor contribution to total cytoplasmic NADH

doi:10.1128/jb.174.16.5346-5353.1992

Wijtenburg SA, Near J, Korenic SA, Gaston FE, Chen H, Mikkelsen M, et al

This is supported by the fact that the absence of cystine in the culture medium and co-treatment with DHAA efficiently reproduces the effects of IKE + DHAA (Fig