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This can also indirectly prevent downstream inflammation, thus altering disease progression

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doi: 10.1111/dom.14067 177 LiRSheDYeZFangPZongGZhaoYet al

Study Significance of IGF-1 A deregulation or imbalance in the IGF system could have implications in a number of different disorders including perturbations with normal growth, cancer and diabetes

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nonetheless, there are instances where autophagy can promote CSCs to undergo apoptosis, particularly when AMPK is elevated via rottlerin-induced autophagy