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Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases

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Glutathione: Known as the bodys master antioxidant because it aids in the detoxification process at the intracellular level

Mutations in mtDNA disrupt the balance between ROS generation and antioxidant defense systems involving SOD, CAT, and glutathione peroxidase

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