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They also rarely cause a major reaction

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A third mechanism of plaque destabilization known to cause cardiovascular events involves eruption of calcified nodules through the vessel lining and into the lumen, leading to blood clot initiation

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doi: 10.1016/j.phrs.2024.107507, Summary Keywords ferroptosis, iron metabolism, neurodegeneration, Parkinsons disease (PD), therapeutic targets Citation Wang L, Zhang Y and Guo L (2026) Ferroptosis in Parkinsons disease: a review of molecular mechanisms and emerging therapeutic strategies