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The Annals of Pharmacotherapy

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NICE Clinical Knowledge Summaries recommend B12 injections for: Pernicious anaemia an autoimmune condition affecting intrinsic factor production Malabsorption syndromes including coeliac disease and inflammatory bowel disease Post-surgical states particularly following gastrectomy or ileal resection Strict vegan diets when oral supplementation proves inadequate, though oral cyanocobalamin is usually sufficient for dietary deficiency Clinical trials demonstrate that B12 injections rapidly improve haematological parameters and neurological symptoms when deficiency is confirmed through blood tests

This includes mental clarity and general health in addition to physical attributes like vigor and strength

Gonzlez S, Huerta JM, Fernndez S, Patterson AM, Lasheras C

Pregnant or breastfeeding women may not get enough B12 because their bodies need more to support the baby