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Subsequent guidelines further reduced this limit to 71 g per day or 500 g per week, emphasizing that processed meat should be avoided entirely (Mcafee et al., 2010)

However, overdosing may cause digestive issues like diarrhea and gastrointestinal discomfort

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Changes in the PC/PE ratio are known to be associated with ER stress 39

The BE GONE trial results demonstrated that after consuming legumes as prebiotic foods, obese patients with a history of CRC or polyps exhibited an increase in blood levels of pipecolic acid, while indole levels decreased (Zhang et al., 2023)