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Metabolite Set Enrichment Analysis (MSEA) was performed using MetaboAnalyst 6.0 software ( 26 with the following settings: module: enrichment analysis

Their study found that 44.7% of ME/CFS patients had elevated blood lactate at rest which was correlated with increased severity of PEM, although this study did not see a correlation with fatigue severity (Ghali et al., 2019)

doi: van Loon LJC, Schrauwen-Hinderling VB, Koopman R, Wagenmakers AJM, Hesselink MKC, Schaart G, et al

Before using any peptide in a research model, consult the relevant institutional review board, animal-care committee, and biosafety office

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Understanding these pathways is key to choosing the right compound for your research goals