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This little diagram sums it up nicelyits a simple path from a solid powder to a solution you can actually use

Transglutaminase-independent binding of gliadin to intestinal brush border membrane and GM1 ganglioside

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Furthermore, the mechanical strength of the scaffolds is also essential since the matched mechanical properties with cartilage tissue could promote the chondrogenic differentiation of recruited MSCs 22,23

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Its the perfect storm, really, and this combination of increased pressure inside the thin-walled capillary together with a negative alveolar pressure on the other side of the capillary wall creates a huge pressure difference across the capillary wall, causing rupture and EIPH